Article

Carbapenem-resistance <i>oprD</i> mutations reshape <i>Pseudomonas aeruginosa</i> host-pathogen interactions during infection

2025-10-24

Abstract excerpt

Antibiotic resistance is a major global health threat. While its role in reducing drug susceptibility is well established, the broader consequences of resistance mutations on bacterial physiology and behavior during infection remain poorly understood. Carbapenem-resistant Pseudomonas aeruginosa is considered among the highest- priority bacterial threats, with resistance commonly driven by loss-of-function mutatio...

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Literature Corpus work: 21b65285-0f6a-5df7-b5bf-64c67658c8ae
DOI: 10.1101/2025.10.24.684370

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