Article

Mutation-driven evolution of <i>Pseudomonas aeruginosa</i> in the presence of either ceftazidime or ceftazidime/avibactam

2018-06-30

Abstract excerpt

<h4>ABSTRACT</h4> Ceftazidime/avibactam is a combination of beta-lactam/beta-lactamases inhibitor, which use is restricted to some clinical cases including cystic fibrosis patients infected with multidrug resistant Pseudomonas aeruginosa , in which mutation is the main driver of resistance. This study aims to predict the mechanisms of mutation-driven resistance that are selected for when P. aeruginosa is challe...

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Literature Corpus work: 1b4db6d5-7f26-57bd-b9b6-fb6b1a1bd665
DOI: 10.1101/359802

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