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Article

The Role of Multidrug Efflux Pumps in the Antibiotic Resistance of <i>Pseudomonas aeruginosa</i> and Other Gram‐Negative Bacteria

1 Jul 2003

Abstract excerpt

Gram-negative bacteria remain clinically important pathogens in both hospital and community settings. Recent research indicates that efflux pumps play a prominent role in the multidrug resistance of Pseudomonas aeruginosa and many other gram-negative bacteria. Four multidrug efflux pump systems have been well characterized in P. aeruginosa: MexA-MexB-OprM, MexC-MexD-OprJ, MexE-MexF-OprN, and MexX-MexY-OprM. These...

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PMID: 12885104
DOI: 10.1592/phco.23.7.916.32722

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