Article

Implication of DNA methylation changes at chromosome 1q21.1 in the brain pathology of Primary Progressive Multiple Sclerosis

2022-05-07

Abstract excerpt

Multiple Sclerosis (MS) is a heterogeneous inflammatory and neurodegenerative disease of the central nervous system with an unpredictable course toward progressive disability. Understanding and treating progressive MS remains extremely challenging due to the limited knowledge of the underlying mechanisms. We examined the molecular changes associated with primary progressive MS (PPMS) using a cross-tissue (blood an...

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Literature Corpus work: 901325bb-ed87-5f11-ad15-a97e342b5f37
DOI: 10.1101/2022.05.06.22274611

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