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Combining evidence from four immune cell types identifies DNA methylation patterns that implicate functionally distinct pathways during Multiple Sclerosis progression

30 Apr 2019

Abstract excerpt

BACKGROUND: Multiple Sclerosis (MS) is a chronic inflammatory disease and a leading cause of progressive neurological disability among young adults. DNA methylation, which intersects genes and environment to control cellular functions on a molecular level, may provide insights into MS pathogenesis. METHODS: B cells (n = 27) from relapsing-remitting (RRMS), secondary progressive (SPMS) patients and healthy...

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Share to Epigenetics and DNA Methylation
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PMID: 31053557
DOI: 10.1016/j.ebiom.2019.04.042

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