Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular Genetic and Epigenetic Basis of Multiple Sclerosis.

Advances in experimental medicine and biology - 1 Jan 2017

Hojati Zohreh

Abstract excerpt

Multiple Sclerosis (MS) is a chronic immune-mediated disease of spinal cord and brain. The initial event in MS occurs when activated CD4+ T cells in periphery exacerbates immune responses by stimulating immune cells such as B cells, CD8+ cells, mast cells, granulocytes and monocytes. These proinflammatory cells pass blood brain barrier by secreting proinflammatory cytokines including TNF-α and INF-γ which...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Encephalomyelitis, Autoimmune, Experimental
Share to Epigenesis, Genetic
Share to Gene-Environment Interaction

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to TNF gene

Share to Genetic Predisposition to Disease

Share to Multiple Sclerosis

Source

Identifiers

PMID: 28093709
DOI: 10.1007/978-3-319-47861-6_6

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular Genetic and Epigenetic Basis of Multiple Sclerosis.PMID 28093709Read ↗

The potential role of epigenetic modifications in the heritability of multiple sclerosis.Semantic proximity Read ↗

Aberrant DNA methylation profile exacerbates inflammation and neurodegeneration in multiple sclerosis patientsSemantic proximity Read ↗

Epigenetic research in multiple sclerosis: progress, challenges, and opportunitiesSemantic proximity Read ↗

Environmental and genetic risk factors for MS: an integrated reviewSemantic proximity Read ↗

Genes, Gene Loci, and Their Impacts on the Immune System in the Development of Multiple Sclerosis: A Systematic Review.Semantic proximity Read ↗

Epigenetic changes in neurology: DNA methylation in multiple sclerosis.Semantic proximity Read ↗

A Comprehensive Examination of the Role of Epigenetic Factors in Multiple Sclerosis.Semantic proximity Read ↗

An overview of gene-epigenetic-environmental contributions to MS causation.Semantic proximity Read ↗

The genetics of multiple sclerosis: an up-to-date review.Semantic proximity Read ↗

Epigenetic Modifications and Therapy in Multiple Sclerosis.Semantic proximity Read ↗

Genetic Risk in Multiple Sclerosis: Susceptibility, Modifiers and Unresolved QuestionsSemantic proximity Read ↗

Epigenetic mechanisms in multiple sclerosis: implications for pathogenesis and treatmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.