Article

Expression of PGK1 in Breast Cancers Alters Their Sensitivity to Ferroptosis Induction via Metabolic Reprogramming

2025-09-10

Abstract excerpt

<title>Abstract</title> <p>Therapeutic resistance and recurrence are among the major contributors to poor outcomes for patients with breast cancer. Induction of ferroptosis, a form of cellular death characterized by toxic lipid peroxide overload, has emerged as a promising therapeutic strategy against breast cancers including triple-negative breast cancer(TNBC). Nevertheless, certain types of cancer are imperviou...

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Literature Corpus work: 8fdc896c-e1b7-5bc2-b69d-54e761040253
DOI: 10.21203/rs.3.rs-7323200/v1

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