Article
Systematic Analysis Uncovers Associations of PGK1 with Prognosis and Immunological Characteristics in Breast Cancer.
Disease markers - 1 Jan 2021
Li Liangdong, Bai Yang, Gao Yang, Li Deheng, Chen Lei, Zhou Changshuai, Feng Mingtao, Chen Xin, Jin Wei, Cao Yiqun
Abstract excerpt
OBJECTIVE: Phosphoglycerate kinase 1 (PGK1) is an essential enzyme in the process of glycolysis and mitochondrial metabolism. Herein, we conducted a systematic analysis to uncover the clinical implication of PGK1 deregulation in breast cancer. METHODS: Expression pattern and prognostic significance of PGK1 were comprehensively assessed across pan-cancer based on RNA-seq profiles from the TCGA project....
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