Article

Indirubin suppresses 4T1 murine breast cancer in vitro and in vivo by induction of ferroptosis and up-regulation of Ptgs2

2021-04-09

Abstract excerpt

<title>Abstract</title> <p>Background Indirubin, isolated from <italic>Indigo Naturals</italic>, is reported to have the inhibitory activity of MCF-7 human breast cancer cells <italic>in vitro</italic>. However, studies on its anti-breast cancer activity <italic>in vivo</italic> and underlying mechanism are insufficient. We explored whether indirubin could trigger ferroptosis of breast cancer cells to exert anti...

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Literature Corpus work: a0073e64-17bb-5386-8feb-cd4559753e30
DOI: 10.21203/rs.3.rs-390546/v1

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