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Halicin Reduces the Warburg Effect and Overcomes Drug Resistance by Activating the Pyruvate Kinase M2 Pathway for Triple-Negative Breast Cancer Treatment

6 Jun 2025

Abstract excerpt

High Resolution Image Download MS PowerPoint Slide Breast cancer represents the most common cancer among women worldwide. Triple-negative breast cancer (TNBC), a particularly aggressive, metastatic, and drug-resistant subtype of breast cancer, poses a significant clinical challenge because of its resistance to treatment. The efficacy of commonly employed chemotherapeutic agents, such as paclitaxel, is severely...

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PMID: 40547617
DOI: 10.1021/acsomega.5c01251

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