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Clinical biology of OPCML and its potential therapeutic applications in ovarian and breast cancers

2015-01-01

Abstract excerpt

Opioid binding protein cell adhesion molecule like (OPCML), is a glycosyl phosphatidylinositol (GPI) anchored cell adhesion molecule, that was discovered by our lab to be somatically methylated with its expression silenced in over 80% of epithelial ovarian cancers (EOCs) (Sellar, Watt et al. 2003). This was subsequently confirmed and further expanded by other groups to include many other tumours (Czekierdowski, Cz...

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Literature Corpus work
8f35af6f-aaaa-511d-84a6-c9f3e7741615
DOI
10.25560/47978
Open publication

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