Article

Functional characterisation of OPCML clinical mutations in ovarian cancer and correlate to OPCML crystal structure

2018-01-01

Abstract excerpt

Ovarian cancer is a heterogeneous disease, considered the most lethal of all gynaecological malignancies. With an initially high response rate to treatment, ovarian cancer can suddenly relapse, with advanced stages showing loco-regional dissemination. Despite enormous efforts to tackle ovarian cancer, current treatments fail to bring complete remission or significantly extend patient life. OPCML is a promising can...

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Literature Corpus work: 58df0e4c-5e31-52df-a5d4-71036cfaf558
DOI: 10.25560/68395

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