Article
OPCML at 11q25 is epigenetically inactivated and has tumor-suppressor function in epithelial ovarian cancer.
Nature genetics - 1 Jul 2003
Sellar Grant C, Watt Karen P, Rabiasz Genevieve J, Stronach Euan A, Li Li, Miller Eric P, Massie Charles E, Miller Jayne, Contreras-Moreira Bruno, Scott Diane, Brown Iain, Williams Alastair R, Bates Paul A, Smyth John F, Gabra Hani
Abstract excerpt
Epithelial ovarian cancer (EOC), the leading cause of death from gynecological malignancy, is a poorly understood disease. The typically advanced presentation of EOC with loco-regional dissemination in the peritoneal cavity and the rare incidence of visceral metastases are hallmarks of the diseas...
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