Article

Functional RNA-Seq Profiling of the Tumor Suppressor Gene OPCML in Ovarian Cancers: The Multifunctional, Pleiotropic Impacts of Having Three Ig Domains

2024-12-19

Abstract excerpt

The IgLON Family of Tumor Suppressor Genes (TSG) impact a variety of cellular processes involved in cancer and non-cancer biology. OPCML is a member of this family and as a potent TSG it is commonly silenced in many human cancers and thus an important control point in oncogenesis and tumor growth. Here, we analyze RNA-Seq expression ratios in ovarian cancers from The Cancer Genome Atlas (TCGA) to identify gene set...

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Literature Corpus work: 15ebe5c6-d890-58af-9882-4b2dc98e99c7
DOI: 10.20944/preprints202412.1690.v1

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Functional RNA-Seq Profiling of the Tumor Suppressor Gene OPCML in Ovarian Cancers: The Multifunctional, Pleiotropic Impacts of Having Three Ig DomainsDOI 10.20944/preprints202412.1690.v1Read

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