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TMEM176B inhibits ovarian cancer progression by regulating EMT via the Wnt/β-catenin signaling pathway

19 Mar 2025

Abstract excerpt

BACKGROUND: Ovarian cancer (OC) is recognized as one of the deadliest forms of gynecological cancer, approximately two-thirds of patients have already developed metastasis when they are diagnosed. The function of transmembrane protein 176B (TMEM176B) in the progression of OC remains elusive. This study aimed to investigate the role and molecular mechanism of TMEM176B on OC proliferation and metastasis. METHOD:...

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PMID: 40108613
DOI: 10.1186/s12967-025-06362-0

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