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Article

Loss of the predicted cell adhesion molecule MPZL3 promotes EMT and chemoresistance in ovarian cancer

2024-11-15

Abstract excerpt

Myelin protein zero-like 3 (MPZL3) is an Immunoglobulin-containing transmembrane protein with predicted cell adhesion molecule function. Loss of 11q23, where the MPZL3 gene resides, is frequently observed in cancer, and MPZL3 copy number alterations are frequently detected in tumor specimens. Yet the role and consequences of altered MPZL3 expression have not been explored in tumor development and progression. We...

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Literature Corpus work
4624f74c-8a1e-52b5-88bf-02807089d3db
DOI
10.1101/2024.11.14.623672
Open publication

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Loss of the predicted cell adhesion molecule MPZL3 promotes EMT and chemoresistance in ovarian cancerDOI 10.1101/2024.11.14.623672
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