Article

Single-Cell and Spatial Methods for Multimodal Functional Glycan Profiling in Tissues

2026-02-24

Abstract excerpt

Glycans regulate multiple physiological processes, including immune recognition and cancer progression. In disease, altered glycan landscapes are interpreted by human lectins. Functional glycan-lectin interactions are difficult to profile because glycans are not genome-encoded and their changes are poorly captured by existing multimodal methods. We present two platforms, single-cell outlining and transcriptome seq...

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Literature Corpus work: 8f2f0384-0a4b-58f2-9376-1ce46d636400
DOI: 10.64898/2026.02.23.707224

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