scRepertoire 2: Enhanced and Efficient Toolkit for Single-Cell Immune Profiling

Abstract excerpt

Single-cell adaptive immune receptor repertoire sequencing (scAIRR-seq) and single-cell RNA sequencing (scRNA-seq) provide a transformative approach to profiling immune responses at unprecedented resolution across diverse pathophysiologic contexts. This work presents scRepertoire 2, a substantial update to our R package for analyzing and visualizing single-cell immune receptor data. This new version introduces an...

Topics

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• Cancer Immunotherapy and Biomarkers
• Genetic Variation
• High-Throughput Nucleotide Sequencing
• Immunogenetics
• Immunoglobulins
• Receptors, Antigen, T-Cell
• Single-cell and spatial transcriptomics
• Software

Identifiers and source

Literature Corpus work

9e414779-a5b5-527e-bfa9-7d27c73c4845

DOI

10.1101/2024.12.31.630854