Article

White Matter Hyperintensities Precede other Biomarkers in <i>GRN</i> Frontotemporal Dementia

2025-04-03

Abstract excerpt

<h4>INTRODUCTION</h4> Increased white matter hyperintensities (WMHs) have been reported in genetic frontotemporal dementia (FTD) in small studies, but the sequence of WMH abnormalities relative to other biomarkers is unclear. <h4>METHODS</h4> Using a large dataset (n=763 GENFI2 participants), we measured WMHs and examined them across genetic FTD variants and stages. Cortical and subcortical volumes were parcella...

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Literature Corpus work: 8f271bb5-06bb-5fba-a54a-61de7528abd8
DOI: 10.1101/2025.03.31.646450

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