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Article

White matter hyperintensities are seen only in GRN mutation carriers in the GENFI cohort

1 Jan 2017

Abstract excerpt

Genetic frontotemporal dementia is most commonly caused by mutations in the progranulin (GRN), microtubule-associated protein tau (MAPT) and chromosome 9 open reading frame 72 (C9orf72) genes. Previous small studies have reported the presence of cerebral white matter hyperintensities (WMH) in genetic FTD but this has not been systematically studied across the different mutations. In this study WMH were assessed...

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PMID: 28529873
DOI: 10.1016/j.nicl.2017.04.015

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