Article

Molecular insights into biogenesis of glycosylphosphatidylinositol anchor proteins

2022-03-01

Abstract excerpt

<title>Abstract</title> <p>Eukaryotic cells are coated with an abundance of glycosylphosphatidylinositol anchor proteins (GPI-APs) that play crucial roles in fertilization, neurogenesis, and immunity. Covalent addition of structurally diverse GPI anchorages at the carboxyl termini of target proteins is catalyzed by an endoplasmic reticulum integral membrane GPI transamidase complex (GPI-T) conserved among all euk...

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Literature Corpus work: 8f22fd92-b31b-5057-984e-5d76ce3b3f14
DOI: 10.21203/rs.3.rs-1339620/v1

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