Article
Characterisation of the enzymatic complex for the first step in glycosylphosphatidylinositol biosynthesis.
The international journal of biochemistry & cell biology - 1 Mar 2000
Tiede A, Nischan C, Schubert J, Schmidt R E
Abstract excerpt
The mammalian N-acetylglucosaminyl transferase for the first step in glycosylphosphatidylinositol biosynthesis has been shown to consist of at least four components: PIG-A, PIG-C, PIG-H and GPI1. Here, the enzymatic complex is further characterised. PIG-A protein, which is thought to represent the catalytic subunit of the complex, was expressed in an epitope-tagged form in the PIG-A deficient JY5 lymphoblastoid...
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