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GPI Transamidase and GPI anchored proteins: Oncogenes and biomarkers for cancer

27 Aug 2013

Abstract excerpt

Cancer is second only to heart disease as a cause of death in the US, with a further negative economic impact on society. Over the past decade, details have emerged which suggest that different glycosylphosphatidylinositol (GPI)-anchored proteins are fundamentally involved in a range of cancers. This post-translational glycolipid modification is introduced into proteins via the action of the enzyme GPI...

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PMID: 23978072
DOI: 10.3109/10409238.2013.831024

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