Article

Unraveling the intracellular cross-talk governing the balance between TNF <i>α</i> mediated survival and apoptosis signaling

2021-09-08

Abstract excerpt

Tumor necrosis factor alpha (TNF α ), a pleiotropic cytokine, helps maintain a balance between proliferation and apoptosis in normal cells. This balance is often sacrificed in a diseased cell, such as that of a cancer, by preferring survival phenotype over apoptosis. Restoring this balance requires a detailed understanding of the causal intracellular mechanisms that govern TNF α stimulated apoptotic response. In...

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Literature Corpus work: 8f1f9a92-93a3-53d8-8ffe-21c43caa4ce8
DOI: 10.1101/2021.09.07.459274

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