Article

Pulmonary Hypertension in Sickle Cell Disease: Novel Findings of Gene Polymorphisms Related to Pathophysiology

2024-04-01

Abstract excerpt

Pulmonary hypertension (PH) is a progressive and potentially fatal complication of sickle cell disease (SCD) affecting 6-10% of adult SCD patients. Various mechanisms and theories have been evaluated to explain the pathophysiology of the disease. However, questions remain, particularly regarding the clinical heterogeneity of the disease in terms of symptoms, complications, and survival. Beyond the classical mechan...

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Literature Corpus work: 8ef7dfb4-6540-500f-bdfa-e3a4ff5c66e9
DOI: 10.20944/preprints202404.0049.v1

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