Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impact of Genetic Variations on Thromboembolic Risk in Saudis with Sickle Cell Disease.

Genes - 9 Oct 2023

Alshabeeb Mohammad A, Alwadaani Deemah, Al Qahtani Farjah H, Abohelaika Salah, Alzahrani Mohsen, Al Zayed Abdullah, Al Saeed Hussain H, Al Ajmi Hala, Alsomaie Barrak, Rashid Mamoon, Daly Ann K

Abstract excerpt

BACKGROUND: Sickle cell disease (SCD) is a Mendelian disease characterized by multigenic phenotypes. Previous reports indicated a higher rate of thromboembolic events (TEEs) in SCD patients. A number of candidate polymorphisms in certain genes (e.g., FVL, PRT, and MTHFR) were previously reported as risk factors for TEEs in different clinical conditions. This study aimed to genotype these genes and other loci...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anemia, Sickle Cell
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Haplotypes

Share to Neoplasm Proteins

Share to Polymorphism, Single Nucleotide

Share to Receptors, Odorant

Source

Open in PubMed Open full text

Identifiers

PMID: 37895268
DOI: 10.3390/genes14101919
PMCID: PMC10606407

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impact of Genetic Variations on Thromboembolic Risk in Saudis with Sickle Cell Disease.PMID 37895268Read ↗

Pulmonary Hypertension in Sickle Cell Disease: Novel Findings of Gene Polymorphisms Related to PathophysiologySemantic proximity Read ↗

Pulmonary Hypertension in Sickle Cell Disease: Novel Findings of Gene Polymorphisms Related to Pathophysiology.Semantic proximity Read ↗

The current state of sickle cell trait: implications for reproductive and genetic counselingSemantic proximity Read ↗

The current state of sickle cell trait: implications for reproductive and genetic counselingSemantic proximity Read ↗

Utilizing Whole-Exome Sequencing to Characterize the Phenotypic Variability of Sickle Cell Disease.Semantic proximity Read ↗

Frequency of thrombophilic genetic polymorphisms among Saudi subjects compared with other populations.Semantic proximity Read ↗

The Saudi Thrombosis and Familial Thrombophilia Registry. Design, rational, and preliminary results.Semantic proximity Read ↗

Environmental and Genetic Risk Factors Associated with Venous Thromboembolism.Semantic proximity Read ↗

Venous thromboembolism incidence in the Cooperative Study of Sickle Cell Disease.Semantic proximity Read ↗

Epidemiology of sickle cell disease in Saudi Arabia.Semantic proximity Read ↗

Genetic Variation and Sickle Cell Disease Severity: A Systematic Review and Meta-Analysis.Semantic proximity Read ↗

Interplay Between Sickle Cell Disease and Thrombosis: Pathophysiology and Potential Risk Factors. A Single Center ExperienceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.