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Article

Genomic polymorphisms in sickle cell disease: implications for clinical diversity and treatment.

Expert review of hematology - 1 Aug 2010

Fertrin Kleber Yotsumoto, Costa Fernando Ferreira

Abstract excerpt

Sickle cell disease (SCD) is one of the best characterized human monogenic disorders. The development of molecular biology allowed the identification of several genomic polymorphisms responsible for its clinical diversity. Research on the first genetic modulators of SCD, such as coinheritance of α-thalassemia and haplotypes in the β-globin gene cluster, have been followed by studies associating single nucleotide...

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Source

Identifiers

PMID: 21083035
DOI: 10.1586/ehm.10.44

Genes

SCD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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