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Article

Pulmonary Hypertension in Sickle Cell Disease: Novel Findings of Gene Polymorphisms Related to Pathophysiology.

International journal of molecular sciences - 27 Apr 2024

Chatzidavid Sevastianos, Flevari Pagona, Tombrou Ioanna, Anastasiadis Georgios, Dimopoulou Maria

Abstract excerpt

Pulmonary hypertension (PH) is a progressive and potentially fatal complication of sickle cell disease (SCD), affecting 6-10% of adult SCD patients. Various mechanisms and theories have been evaluated to explain the pathophysiology of this disease. However, questions remain, particularly regarding the clinical heterogeneity of the disease in terms of symptoms, complications, and survival. Beyond the classical...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hemoglobinopathies and Related Disorders

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Share to Myeloproliferative Neoplasms: Diagnosis and Treatment

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Source

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Identifiers

PMID: 38732015
DOI: 10.3390/ijms25094792
PMCID: PMC11084253

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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