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Article

Genetic etiologies for phenotypic diversity in sickle cell anemia.

TheScientificWorldJournal - 18 Jan 2009

Steinberg Martin H

Abstract excerpt

The clinical course of patients with sickle cell anemia, a Mendelian trait, is characteristically highly variable. HbF concentration and the presence of á thalassemia are established modulators of the disease, but cannot account for all of its clinical heterogeneity. To find additional genetic modulators of disease, genotype-phenotype association studies, where single nucleotide polymorphisms (SNPs) in candidate...

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Share to alpha-Thalassemia
Share to Anemia, Sickle Cell
Share to Fetal Hemoglobin

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19151898
DOI: 10.1100/tsw.2009.10
PMCID: PMC5823205

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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