Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mechanisms of Resistance to Small Molecules in Acute Myeloid Leukemia

15 Sept 2023

Abstract excerpt

In recent years, great progress has been made in the therapy of AML by targeting cellular processes associated with specific molecular features of the disease. Various small molecules inhibiting FLT3, IDH1/IDH2, and BCL2 have already gained approval from the respective authorities and are essential parts of personalized therapeutic regimens in modern therapy of AML. Unfortunately, primary and secondary resistance...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Myeloid Leukemia Research
Share to Histone Deacetylase Inhibitors Research
Share to Protein Degradation and Inhibitors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37760544
DOI: 10.3390/cancers15184573

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mechanisms of Resistance to Small Molecules in Acute Myeloid LeukemiaPMID 37760544Read ↗

Update on Small Molecule Targeted Therapies for Acute Myeloid Leukemia.Semantic proximity Read ↗

Precision medicine in AML: overcoming resistance.Semantic proximity Read ↗

Resistance to FLT3 inhibitors in acute myeloid leukemia: Molecular mechanisms and resensitizing strategiesSemantic proximity Read ↗

Mechanisms of drug resistance in acute myeloid leukemiaSemantic proximity Read ↗

The Molecular Mechanisms of Resistance to IDH Inhibitors in Acute Myeloid LeukemiaSemantic proximity Read ↗

Mechanisms responsible for therapy resistance of acute myelogenous leukemia (AML).Semantic proximity Read ↗

Mechanisms of drug resistance in AML.Semantic proximity Read ↗

Secondary mutations as mediators of resistance to targeted therapy in leukemia.Semantic proximity Read ↗

Novel Therapeutics in Acute Myeloid Leukemia.Semantic proximity Read ↗

Resistance to targeted therapies in acute myeloid leukemia.Semantic proximity Read ↗

Molecular and chromosomal alterations: new therapies for relapsed acute myeloid leukemia.Semantic proximity Read ↗

Emerging small molecular inhibitors as targeted therapies for high-risk acute myeloid leukemias.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.