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Article

Non-Coding RNAs Are Implicit in Chronic Myeloid Leukemia Therapy Resistance

14 Oct 2022

Abstract excerpt

Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm initiated by the presence of the fusion gene BCR::ABL1. The development of tyrosine kinase inhibitors (TKIs) highly specific to p210BCR-ABL1, the constitutively active tyrosine kinase encoded by BCR::ABL1, has greatly improved the prognosis for CML patients. Now, the survival rate of CML nearly parallels that of age matched controls. However, therapy...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36293127
DOI: 10.3390/ijms232012271

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