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The RNA N⁶-Methyladenosine Methylome Coordinates Long Non-Coding RNAs to Mediate Cancer Drug Resistance by Activating PI3K Signaling

2024-12-18

Abstract excerpt

<title>Abstract</title> <p>Long non-coding RNAs (lncRNAs) and RNA N⁶-methyladenosine (m<sup>6</sup>A) have been linked to leukemia drug resistance. However, whether and how lncRNAs and m<sup>6</sup>A coordinately regulate resistance remain elusive. Here, we show that many differentially expressed lncRNAs enrich m<sup>6</sup>A, and more lncRNAs tend to have higher m<sup>6</sup>A content in CML cells resistant to t...

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Literature Corpus work
67404a38-cb79-5109-98d0-ab1da13d0302
DOI
10.21203/rs.3.rs-5663230/v1
Open publication

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The RNA N⁶-Methyladenosine Methylome Coordinates Long Non-Coding RNAs to Mediate Cancer Drug Resistance by Activating PI3K SignalingDOI 10.21203/rs.3.rs-5663230/v1
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