Article

Redox regulation of neuroinflammatory pathways contributes to damage in Alzheimer’s disease brain

2025-09-09

Abstract excerpt

The mechanism(s) whereby redox stress mediates aberrant immune signaling in age-related neurological disorders remains largely unknown. Normally, the innate immune system mounts a robust response to infectious stimuli. However, unintentional activation by host-derived factors, such as aggregated proteins associated with neurodegenerative disorders or by cytoplasmic genomic or mitochondrial DNA, can elicit aberrant...

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Literature Corpus work: 8e49e1a7-6a32-5153-93fc-37f39460df6d
DOI: 10.1101/2025.09.08.674963

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