Article

Infection, inflammation & innate immunity in the paediatric CF airway

2016-01-01

Abstract excerpt

This thesis focuses on infection and immunity within the airways in cystic fibrosis (CF), particularly the role of the antimicrobial peptides (part of the innate immune system) and their relationship to vitamin D status. Vitamin D response elements have been identified in the genes encoding the antimicrobial peptides cathelicidin (LL37) and human β defensins (HBD-2) and in-vitro vitamin D significantly induces exp...

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Literature Corpus work: 8deca1b1-6c54-514a-b45c-c0263c91f56e
DOI: 10.25560/43757

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