Article

Exploring the relationship between loss of CFTR protein function and markers of disease severity in chronic suppurative lung disease

2018-01-01

Abstract excerpt

Cystic fibrosis (CF) and Primary Ciliary Dyskinesia (PCD) are chronic suppurative lung diseases (CSLD). CF is characterised by inherited mutations affecting the cystic fibrosis transmembrane regulator (CFTR) protein, which is thought to be normal in PCD, however the role of CFTR in disease is incompletely understood. This thesis investigates the relationship between CFTR, inflammation and airway health, firstly in...

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Literature Corpus work: 4e5a7ce5-993a-5086-92df-7b861029a399
DOI: 10.25560/57500

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