Article
What's new in CF airway inflammation: an update.
Paediatric respiratory reviews - 1 Jan 2006
Ratjen Felix
Abstract excerpt
Neutrophilic airway inflammation is a characteristic feature of cystic fibrosis (CF) lung disease and present in most patients with pulmonary manifestations of the disease. Here we discuss the ongoing controversy whether the CFTR mutation itself causes a pro-inflammatory milieu in the airways or whether inflammation is always secondary to infection. Since the presence of inflammation has been shown to be a risk...
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