Series Introduction: Intrinsic and innate defenses in the lung: intersection of pathways regulating lung morphogenesis, host defense, and repair

Abstract excerpt

This Perspective series seeks to summarize the present concepts regarding the biological processes that mediate intrinsic and innate host defense against microbial invasion of the lung. From an evolutionary standpoint, the requirements for an extensive gas exchange region that comes in direct contact with inhaled particles and pathogens present a formidable challenge that has been countered by the layering and...