Article
Mucosal Immunity in Cystic Fibrosis.
Journal of immunology (Baltimore, Md. : 1950) - 15 Dec 2021
Bojanowski Christine M, Lu Shiping, Kolls Jay K
Abstract excerpt
The highly complex and variable genotype-phenotype relationships observed in cystic fibrosis (CF) have been an area of growing interest since the discovery of the CF transmembrane conductance regulator (CFTR) gene >30 y ago. The consistently observed excessive, yet ineffective, activation of both the innate and adaptive host immune systems and the establishment of chronic infections within the lung, leading to...
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