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Article

Mapping Pulmonary and Systemic Inflammation in Preschool Aged Children With Cystic Fibrosis.

Frontiers in immunology - 1 Jan 2021

Shanthikumar Shivanthan, Ranganathan Sarath C, Saffery Richard, Neeland Melanie R

Abstract excerpt

The immune landscape of the paediatric respiratory system remains largely uncharacterised and as a result, the mechanisms of globally important childhood respiratory diseases remain poorly understood. In this work, we used high parameter flow cytometry and inflammatory cytokine profiling to map the local [bronchoalveolar lavage (BAL)] and systemic (whole blood) immune response in preschool aged children with...

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Identifiers

PMID: 34721395
DOI: 10.3389/fimmu.2021.733217
PMCID: PMC8554310

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