Article

The human developing cerebral cortex is characterized by an increased de novo expression of lncRNAs in excitatory neurons

2023-10-26

Abstract excerpt

<h4>Background</h4> Outstanding human cognitive abilities are computed in the cerebral cortex, a mammalian-specific brain region and the place of massive biological innovation. Long noncoding RNAs (lncRNAs) have emerged as gene regulatory elements with higher evolutionary turnover than mRNAs. The many lncRNAs identified in neural tissues make them candidates for molecular sources of cerebral cortex evolution and...

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Literature Corpus work: e9c3b4ba-4379-58b1-bc16-d2ccc0c0e693
DOI: 10.1101/2023.10.26.564246

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