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Article

IL-18 and IL-18BP: A Unique Dyad in Health and Disease

2024-11-12

Abstract excerpt

Interleukin-18 (IL-18) serves a dual function in the immune system, acting as a "double-edged sword" cytokine. Depending on the microenvironment and timing, IL-18 can either drive harmful inflammation or restore immune homeostasis. Pathologies characterized by elevated IL-18, known as IL-18’opathies, highlight the therapeutic potential for IL-18 blockade. IL-18 Binding Protein (IL-18BP) is one of only fo...

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Identifiers and source

Literature Corpus work
8de2016a-2f1a-5707-810b-d1cd6416676a
DOI
10.20944/preprints202411.0864.v1
Open publication

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IL-18 and IL-18BP: A Unique Dyad in Health and DiseaseDOI 10.20944/preprints202411.0864.v1
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