Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IL-1, IL-18, and IL-33 families of cytokines.

Immunological reviews - 1 Jun 2008

Arend William P, Palmer Gaby, Gabay Cem

Abstract excerpt

SUMMARY: The interleukin-1 (IL-1), IL-18, and IL-33 families of cytokines are related by mechanism of origin, receptor structure, and signal transduction pathways utilized. All three cytokines are synthesized as precursor molecules and cleaved by the enzyme caspase-1 before or during release from the cell. The NALP-3 inflammasome is of crucial importance in generating active caspase-1. The IL-1 family contains...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Interleukin-33
Share to Interleukins
Share to Immune System Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-1

Share to Interleukin-18

Share to NLR Family, Pyrin Domain-Containing 3 Protein

Share to Receptors, Interleukin-1

Share to Th2 Cells

Source

Identifiers

PMID: 18613828
DOI: 10.1111/j.1600-065X.2008.00624.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IL-1, IL-18, and IL-33 families of cytokines.PMID 18613828Read ↗

Interleukins (from IL-1 to IL-38), interferons, transforming growth factor β, and TNF-α: Receptors, functions, and roles in diseasesSemantic proximity Read ↗

Identification of Constitutively Active Interleukin 33 (IL-33) Splice VariantSemantic proximity Read ↗

[Inflammasome and interleukin 1].Semantic proximity Read ↗

The tetrapeptide sequence of IL-18 and IL-1β regulates their recruitment and activation by inflammatory caspasesSemantic proximity Read ↗

[Interleukin-1, inflammasome and autoinflammatory diseases].Semantic proximity Read ↗

IL-12 Family Cytokines: General Characteristics, Pathogenic Microorganisms, Receptors, and Signalling PathwaysSemantic proximity Read ↗

New dog and new tricks: evolving roles for IL-33 in type 2 immunitySemantic proximity Read ↗

IL-33 and IL-33 Receptors in Host Defense and DiseasesSemantic proximity Read ↗

The IL-33/IL-31 Axis in Allergic and Immune-Mediated DiseasesSemantic proximity Read ↗

Interleukin‐33 in allergySemantic proximity Read ↗

Biology of IL-36 cytokines and their role in diseaseSemantic proximity Read ↗

IL-1 and IL-18 receptors, and their extended familySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.