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Article

Structure and function of interleukin-17 family cytokines

1 Jan 2011

Abstract excerpt

The recently identified interleukin-17 (IL-17) cytokines family, which comprises six members in mammals (IL-17A-F), plays essential roles in the host immunity against infectious diseases and chronic inflammatory diseases. The three-dimensional structures containing IL-17A or IL-17F have become available and revealed the unique structural features of IL-17s as well as their receptors. Molecular modeling in this...

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PMID: 21337007
DOI: 10.1007/s13238-011-1006-5

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