Article

Identification of GLP1R and MCHR1 signaling as novel GPCR targets of MRAP2 protein

2022-03-30

Abstract excerpt

The seven trans-membrane spanning G protein couple receptors(GPCRs) constitute the largest family of FDA approved drug targets to treat numerous human diseases, including metabolic associated disorders. The Melanocortin Receptor Accessory Protein 2 (MRAP2), a small single transmembrane protein broadly expressed in multiple tissues has been defined as a vital endocrine pivot of five melanocortin receptors(MC1R-MC5R...

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Literature Corpus work: 8d872350-79bb-5466-9483-2754ce280af1
DOI: 10.22541/au.164864751.12434243/v1

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