Article

Large-scale PTM analysis reveals that the E3 ligase, Anaphase promoting complex, APC/C, is a master regulator of protein complexes containing GIGYF2.

2025-04-11

Abstract excerpt

<title>Abstract</title> <p><bold>GIGYF2 is one of several uncertain candidates in Parkinson’s disease (PD) since follow-on studies did not confirm the findings from large scale genetics analyses. This report shows that post translational modifications (PTMs) of GIGYF2 and additional proteins or PD candidates with which it complexes are regulated by the E3 ligase Anaphase promoting complex (APC/C) in HEK293T cells...

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Literature Corpus work: 8d3c7431-0f6e-5139-a02f-4568eab466ee
DOI: 10.21203/rs.3.rs-6378554/v1

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Large-scale PTM analysis reveals that the E3 ligase, Anaphase promoting complex, APC/C, is a master regulator of protein complexes containing GIGYF2.DOI 10.21203/rs.3.rs-6378554/v1Read

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