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Induction of mitophagy reverts age-associated decline of the hematopoietic and immune systems

2023-03-31

Abstract excerpt

<h4>ABSTRACT</h4> Aging compromises hematopoietic and immune system functions, making elderly individuals especially susceptible to hematopoietic failure, infections and tumor development and thus representing an important medical target for a broad range of diseases. During aging, hematopoietic stem cells (HSCs) lose their blood reconstitution capability and commit preferentially toward myeloid lineage (myeloid-...

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Literature Corpus work
d8818ef2-e752-5f92-9372-0c825a7f657d
DOI
10.1101/2023.03.30.534925
Open publication

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Induction of mitophagy reverts age-associated decline of the hematopoietic and immune systemsDOI 10.1101/2023.03.30.534925
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