Article

Atypical Hemolytic Uremic Syndrome During Induction Chemotherapy in Neuroblastoma, a Rare Phenomenon or Common Congenital Predisposition?

2024-05-05

Abstract excerpt

Atypical hemolytic uremic syndrome (aHUS) is an infrequently encountered complement-mediated thrombotic microangiopathy (TMA) usually associated with germline variants in genes of the complement system. Clinical findings of microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury (AKI) with severe hypertension arise due to aberrant complement protein activation in the circulation and significan...

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Literature Corpus work: 8cea41a4-2c0d-5437-826f-249fe65f0acb
DOI: 10.22541/au.171490119.98413796/v1

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