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Immunomodulatory Effects of a Cell Processing Device: Insights from Single Cell RNA Sequencing and Gene Set Enrichment Analysis

2025-10-06

Abstract excerpt

The Selective Cytopheretic Device (SCD), marketed as QUELimmune TM , is an autologous leukocyte processing extracorporeal device which promotes immunomodulation of a systemic hyperinflammatory states. To date, interrogation of the mechanism of action (MoA) of this cell-directed therapy has provided insight into therapeutic impact on neutrophils. However, characterization of monocytes has proven to be more difficu...

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Literature Corpus work
8c9ca03f-809f-57e6-9c54-dda52a7611bd
DOI
10.1101/2025.10.03.680363
Open publication

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Immunomodulatory Effects of a Cell Processing Device: Insights from Single Cell RNA Sequencing and Gene Set Enrichment AnalysisDOI 10.1101/2025.10.03.680363
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