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The Acute Effects of Lipoprotein Apheresis on Monocyte Subset Distribution and Transcriptome in Patients With and Without Elevated Lipoprotein(a)

2025-06-09

Abstract excerpt

Lipoprotein apheresis effectively lowers low density lipoprotein and lipoprotein(a) extracorporeally. Both low density lipoprotein and lipoprotein(a) are causal risk factors for cardiovascular disease and interact with monocytes in the circulation, although the latter is the predominant lipoprotein carrier of pro-inflammatory oxidized phospholipids and considered to be a much more potent direct activator of monocy...

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Literature Corpus work
413de63f-74c3-539b-af6b-60d061acb27c
DOI
10.1101/2025.06.08.25328552
Open publication

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The Acute Effects of Lipoprotein Apheresis on Monocyte Subset Distribution and Transcriptome in Patients With and Without Elevated Lipoprotein(a)DOI 10.1101/2025.06.08.25328552
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