Article

Leveraging AlphaFold 3 for Structural Modeling of Neurological Disorder-Associated Proteins: A Pathway to Precision Medicine

2024-11-20

Abstract excerpt

Accurate structural modeling of neurological disorder-causing proteins provides an important layer in unraveling the mechanism of disease and identifying therapeutic targets. This study utilizes AlphaFold 3, a state-of-the-art protein structure prediction platform, to model and interpret cis- and trans-pQTL-derived proteins associated with Alzheimer’s disease, Parkinson’s disease, and stroke. Using the NG00102 dat...

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Literature Corpus work: 8c2c73cc-1cc6-5a32-b122-31c5262866e2
DOI: 10.1101/2024.11.18.624211

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